Survodutide + Tirzepatide
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40
authors mention this stack
20
ran the components concurrently
Survodutide + Tirzepatide (Survodutide + Tirzepatide) appears in 40 author journeys (20 as actual concurrent use). Common goals: weight loss / appetite suppression; weight loss; stop weight loss plateau. Typical doses reported: Survodutide 1.2mg, Tirzepatide 10mg. Reported side effects include: increased resting heart rate Research: 6 studies discuss two or more of these components together (5 clinical); the components appear across 504 studies in total.
Research support
6 research studies discuss two or more of these components together (5 clinical). Per-component literature:
PubMed/PMC articles mentioning each compound in title or abstract.
Typical doses reported
Community-reported doses are not medical guidance.
How people are running it
12
Currently running
11
Recommended / discussed
10
Planning to run
10
Ran in the past
What people use it for
Sample reported outcomes
- ✓ Blood sugar very rarely drops below 100; glucose levels did not drop any lower than they were on tirzepatide alone.
- ✓ No weight loss, and food noise eventually returned, leading to weight regain
- ✓ Scale began going down again; the combo works rather well.
- ✓ Successfully broke a two-month weight stall (weight dropped from 278 to 268 lbs) and significantly improved energy levels.
- ✓ Magic bullet, highly convenient, knocks down food noise, keeps suppression going from day 4 to day 7
- ✓ Achieved normal BMI of 24.9, losing 40% of body weight (from 280 lbs to 169 lbs), losing 2.5 lbs per week consistently
- ✓ The protocol stalled and failed to yield further weight loss, prompting a switch to Retatrutide.
- ✓ Helped maintain weight
Self-reported community experiences, not verified results.
Sample reported side effects
- ⚠ increased resting heart rate
- ⚠ None stated
- ⚠ At standard doses: intermittent anhedonia with sharper swings. At accidental 4.0mg Survodutide dose: severe nausea, headache, cold flashes, and sulfur burps. At 10mg Tirzepatide / 3mg Survodutide dose: severe acute reaction including heart palpitations, hot flashes, facial burning, headache, narrowed vision with sparkles/dark spots, prickly sweat, vomiting sensation, bloodshot eyes, splotchy torso with raised red areas, and swollen index fingers.
- ⚠ No tachycardia, resolved the fatigue caused by previous Reta/Cargi stack
- ⚠ Discussion of potential glucagon receptor activation side effects
- ⚠ none mentioned
- ⚠ Stalling, prior history of allodynia/dysesthesia on high-dose Mazdutide
- ⚠ significant constipation ('will back you up pretty good')